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IL-13 barely but significantly decreased elasticity (G’) and viscosity (G”) moduli at 24 hr (Figure . GGE significantly inhibited IL-13-induced MUC5AC secretion in a concentration-dependent manner at 3, 8 and 24 hr, with IC50 values (ninety five% confidence intervals, CI) of 137 (seventy three–102), one hundred thirty (98–one hundred ninety) and ninety six (eighty five–109) μM, respectively (Figure . 4). At 8 and 24 hr, 300 μM GGE decreased secretion beneath the levels of non-IL-13-handled cells, in keeping with our earlier observations . NAC and Amb each considerably lowered the levels of the secreted MUC5AC for some concentrations.
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