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It is commonest in women after the menopause and tends to be progressive, giving rise to the high risk of fractures from minimal trauma.
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The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.
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Zhang et al (2013) stated that estrogen plays essential roles in the regulation of food intake, adiposity, and body weight control.
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Question: Who should be treated with osteoporosis medications?
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Women who had taken the drug had an 86 percent higher risk of atrial fibrillation than those who never took Alendronate (Fosamax), the study found.
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McClung MR, Geusens P, Miller PD, Zippel H, Bensen WG, Roux C, Adami S, Fogelman I, Diamond T, Eastell R, Meunier PJ, Reginster JY, Hip Intervention Program Study Group.
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Three-Year Study of the Fracture Intervention Trial (FIT): a study of patients with at least one baseline vertebral fracture, and 3) Four-Year Study of FIT: a study of patients with low bone mass but without a baseline vertebral fracture.
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FDA MedWatch label change: Atypical fractures update for bisphosphonates (osteoporosis drugs), including alendronate (marketed as Fosamax), alendronate with cholecalciferol (marketed as Fosamax plus D), risedronate (marketed as Actonel and Atelvia), risedronate with calcium carbonate (marketed as Actonel with Calcium), ibandronate (marketed as Boniva), and zoledronic acid (marketed as Reclast).
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