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Does colchicine cause kidney damage? However, in patients with CKD, nonsteroidal anti-inflammatory drugs are not recommended because their use can exacerbate or cause acute kidney injury. Also, colchicine toxicity is increased in patients with CKD, and dosage reduction is required based on level of kidney function.
How soon can you start allopurinol after a gout attack? The sudden lowering of serum urate after starting allopurinol or other ULT often triggers acute gout. Prophylactic colchicine or NSAID is recommended, starting 2 weeks before allopurinol whenever possible, and continuing for 3–6 months to prevent such attacks.
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What is familial Mediterranean fever? Familial Mediterranean fever is a genetic autoinflammatory disorder that causes recurrent fevers and painful inflammation of your abdomen, lungs and joints.
What triggers FMF attacks? It is supposed that physical stresses such as cold exposure, tiredness and emotional stresses could provoke attacks. The most common triggering factors for the attacks with serositis were cold exposure (59.3 %), emotional stress (49.8 %), tiredness (40.0 %) and menstruation (33.7 % in females).


 

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