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What are the main causes of Parkinson's disease? In Parkinson's disease, certain nerve cells (neurons) in the brain gradually break down or die. Many of the symptoms are due to a loss of neurons that produce a chemical messenger in your brain called dopamine. When dopamine levels decrease, it causes abnormal brain activity, leading to symptoms of Parkinson's disease.
What is the prognosis for sufferers of Parkinson's disease? The condition usually worsens over an average of 15 years. The rate of progression and its course varies among patients. The course is relatively benign in some patients with little disability after twenty years and may be more aggressive among others who may be severely disabled after ten years.
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